Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also[edit]. Leprosy · Skin lesion. References[edit]. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.

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Histoid leprosy is an uncommon variant of lepromatous leprosy with characteristic clinical, immunologic, and bacteriologic findings. Family history was non-contributory.

Histoid leprosy – Wikipedia

Support Center Support Center. Closer view of Figure 1 Click here to view.

Dermatol Online J ; They are longer than the normal bacilli, are uniform in length, more often solid, and are arranged in parallel bundles along the long axis of the spindle histiocytes histoid habitus with or without globus formation [ 1 ]. The peripheral nerves may be thickened [ 2 ] or normal [ 5 jistoid.

Corynebacterium diphtheriae Diphtheria Corynebacterium minutissimum Erythrasma Corynebacterium jeikeium Group JK corynebacterium sepsis. Histoid leprosy might represent an enhanced response of the multibacillary disease in localizing the disease process.


The enormous bacillary population in histoid lesions is suggested to be due to focal loss of immunity. View at Google Scholar G. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. Histoid leprosy is a well-recognized entity.


Herein, we present a case of a 37 year old male who presented with skin coloured raised lesions mainly over the trunk, chest, neck and ears in contrast to its usual site of presentation, associated with tingling sensation over the hands and lfprosy.

Case Reports in Pathology. In their most active form, histoid nodules expand rapidly, producing pseudocapsules of compressed collagen at their periphery. Histoid lepromas are sudden eruption of dome shaped lesions usually associated with dapsone resistance, as a variant of lepromatous leprosy or rarely arising de novo.

De-novo Histoid Leprosy

Articles which use infobox templates with no data rows Infobox medical condition new All stub articles. Lepromatous leprosy of histoid type: J Infect Dev Ctries. Introduction Histoid leprosy is a well-recognized entity. Histoid leprosy is a variant of Lepromatous leprosy believed to occur due to a mutant strain of leprosy bacillus called as Histoid Bacillus. By using hkstoid site, you agree to the Terms of Use and Privacy Policy.

Each of them can be differentiated from histoid Hansen on the basis of the characteristic histopathology, absence of mycobacteria on slit skin smear, and nerve thickening. Abstract Histoid leprosy is rare type of lepromatous leprosy characterized by unique clinical, histopathological, and microbiological features.

FNAC is a simple cost-effective method of investigation that is more useful in tuberculoid, lepromatous, and histoid leprosy patients. Our patient was elderly, aged Click on image for details. Srinivasa V Murthy, E-mail: The histopathological features are distinct and contribute to the nomenclature of the condition. Sitemap What’s New Feedback Disclaimer.


Case Reports in Pathology

On dermatological examination, there were multiple grouped skin-colored, well-demarcated, shiny, non-tender nodules, firm to soft in consistency measuring from 0. It is characterized by leprosh or subcutaneous nodules and plaques present over apparently normal skin, with unique histopathological and characteristic bacterial morphology. J Indian Soc Teledermatol ;2: This article has been lerposy by 1 Curcumin could prevent methemoglobinemia induced by dapsone in rats Mateus M.

There was history of low-grade fever for 15 days, associated with redness, pain and discharge from eye, and nasal stuffiness.

Histoid leprosy

Histodi such cases, histoid lesions are transient because the histoid bacilli and the dapsone susceptible M. Although rarely, but it is known to occur at age of ten years or youngerand as old as 84years [ 1 ]. HL has characteristic clinical, histopathological, and bacterial morphological features.

Ananthnarayan R, Panikar CK. He did not take histold form of treatment for his skin lesions. In the past eleven-month treatment, the patient has responded well Figures 1 d and 1 e.

Lesions vary in size and consistency.