Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also[edit]. Leprosy · Skin lesion. References[edit]. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.

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HL has characteristic clinical, histopathological, and bacterial morphological features. Histoid leprosy is not uncommon in Bistoid India. None, Conflict of Interest: Histoid leprosy A Review.

They are considered as mutant bacilli resulting from drug resistance.

Lepromatous leprosy of histoid type Annigeri S R, Metgud S C, Patil J R – Indian J Med Microbiol

Andrews’ Diseases of the Skin: The lesions are usually located on the posterior and lateral aspects of arms, buttocks, thighs, dorsum of hands and on the lower part of the back and over the bony prominences, especially over the elbows and knees [ 2 ]. In the past eleven-month treatment, the patient has responded well Figures 1 d and 1 e.


Palit A, Inamadar AC. Histopathology of the nodule showed atrophic epidermis with a subepidermal grenz zone. Moschella Journal of Cutaneous Pathology.

Case Reports in Pathology

Family history was noncontributory. Histoid, a clinical variant of multibacillary leprosy: FNAC is a simple cost-effective method of investigation that leprosj more useful in tuberculoid, lepromatous, and histoid leprosy patients. Articles which use infobox templates with no data rows Infobox medical condition new All stub articles. Clinically it is characterized by multiple discrete shiny, smooth, painless, succulent, globular, protuberant, firm, skin colored to yellow brown, cutaneous, and, or subcutaneous nodules, papules, and plaques, on apparently normal skin.

Srinivasa V Keprosy, E-mail: Histoid Hansen – A case report. The spindled histiocytes resemble fibroblasts and it is suggested that these fibroblast-like macrophages may have arisen from tissue histiocytes rather than from blood monocytes [ 9 ].

Histoid Leprosy

Discussion Histoid leprosy is considered a variant of lepromatous leprosy[ 2 ] and by others as a distinct entity. Author information Article notes Copyright and License information Disclaimer.

A retrospective study of 40 cases from India. There is male preponderance, and the average age affected is between 21 and 40 years [ 2 ]. Classical histopathological findings include epidermal atrophy as a result of dermal hisoid of the underlying leproma and a grenz zone located immediately below the epidermis.


Histoid Leprosy

Lepromatous leprosy of histoid type. How to cite this article: Histoid leprosy is a distinct and rare variant of lepromatous leprosy, and it was described by Wade 1 in Views Read Edit View history. Support Center Support Center. It is a variant of lepromatous leprosy. Received Oct 20; Accepted Dec There is a leprossy preponderance, and the average age at diagnosis is between 21 and 40 years.

Each of them can be differentiated from histoid Hansen on the basis of the characteristic histopathology, absence of mycobacteria on slit skin smear, and nerve thickening.

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There was no thickening of peripheral nerves.